Abstract
In the past decade, selective C-C and C-heteroatom bond construction through palladium-catalyzed direct C-H bond functionalization has been extensively studied by employing a variety of directing groups. Within this category, direct asymmetric C(sp2)-H and C(sp3)-H activation for the construction of highly enantiomerically enriched skeletons still progressed at a slow pace. This minireview briefly introduces the major advances in the field for palladium-catalyzed direct asymmetric C-H bond functionalization via the directing group strategy.
Original language | English |
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Pages (from-to) | 12616-12632 |
Number of pages | 17 |
Journal | Chemical Science |
Volume | 11 |
Issue number | 47 |
DOIs | |
State | Published - Dec 21 2020 |