Oxidative Mannich Reactions of Tertiary Amines Using a Cu (II) 2-Quinoxalinol Salen Catalyst

Clayton C Black, Anne Gorden

Research output: Contribution to journalArticlepeer-review

Abstract

Oxidative Mannich reactions can be catalyzed using a Cu(II) 2-quinoxalinol salen catalyst and with tert-butyl hydroperoxide (TBHP). Under mild conditions, a range of both cyclic and open chain tertiary amines was tested as substrates, resulting in yields up to 98%.
Original languageEnglish
Pages (from-to)9806--9810
JournalJournal of Organic Chemistry
StatePublished - 2019

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