Oxidative dehydrogenative couplings of pyrazol-5-amines selectively forming azopyrroles

Bo Jiang, Yi Ning, Wei Fan, Shu Jiang Tu, Guigen Li

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

New oxidative dehydrogenative couplings of pyrazol-5-amines for the selective synthesis of azopyrrole derivatives have been described. The former reaction simultaneously installs C-I and N-N bonds through iodination and oxidation, whereas the latter involved a copper-catalyzed oxidative coupling process. The resulting iodo-substituted azopyrroles were employed by treatment with various terminal alkynes through Sonogashira cross-coupling leading to new azo compounds.

Original languageEnglish
Pages (from-to)4018-4024
Number of pages7
JournalJournal of Organic Chemistry
Volume79
Issue number9
DOIs
StatePublished - May 2 2014

Fingerprint Dive into the research topics of 'Oxidative dehydrogenative couplings of pyrazol-5-amines selectively forming azopyrroles'. Together they form a unique fingerprint.

  • Cite this