TY - JOUR
T1 - Numerical simulations of high-frequency respiratory flows in 2D and 3D lung bifurcation models
AU - Parameswaran, Siva
AU - Chen, Zixi
AU - Parameswaran, Shamini
AU - Hu, Yingying
AU - He, Zhaoming
AU - Raj, Rishi
PY - 2014/7/4
Y1 - 2014/7/4
N2 - To better understand the human pulmonary system and optimize the high-frequency oscillatory ventilation (HFOV) design, numerical simulations were conducted under normal breathing frequency and HFOV condition using a CFD code Ansys Fluent and its user-defined C programs. 2D and 3D double bifurcating lung models were created, and the geometry corresponds to fifth to seventh generations of airways with the dimensions based on the Weibel's pulmonary model. Computations were carried out for different Reynolds numbers (Re = 400 and 1000) and Womersley numbers (α; = 4 and 16) to study the air flow fields, gas transportation, and wall shear stresses in the lung airways. Flow structure was compared with experimental results. Both 2D and 3D numerical models successfully reproduced many results observed in the experiment. The oxygen concentration distribution in the lung model was investigated to analyze the influence of flow oscillation on gas transport inside the lung model.
AB - To better understand the human pulmonary system and optimize the high-frequency oscillatory ventilation (HFOV) design, numerical simulations were conducted under normal breathing frequency and HFOV condition using a CFD code Ansys Fluent and its user-defined C programs. 2D and 3D double bifurcating lung models were created, and the geometry corresponds to fifth to seventh generations of airways with the dimensions based on the Weibel's pulmonary model. Computations were carried out for different Reynolds numbers (Re = 400 and 1000) and Womersley numbers (α; = 4 and 16) to study the air flow fields, gas transportation, and wall shear stresses in the lung airways. Flow structure was compared with experimental results. Both 2D and 3D numerical models successfully reproduced many results observed in the experiment. The oxygen concentration distribution in the lung model was investigated to analyze the influence of flow oscillation on gas transport inside the lung model.
KW - CFD
KW - Gas transport
KW - HFOV
KW - Lung bifurcation model
UR - http://www.scopus.com/inward/record.url?scp=84903193287&partnerID=8YFLogxK
U2 - 10.1080/15502287.2014.904454
DO - 10.1080/15502287.2014.904454
M3 - Article
AN - SCOPUS:84903193287
SN - 1550-2287
VL - 15
SP - 337
EP - 344
JO - International Journal of Computational Methods in Engineering Science and Mechanics
JF - International Journal of Computational Methods in Engineering Science and Mechanics
IS - 4
ER -