Novel imidazolination reaction of alkenes provides an easy access to new α,β-differentiated 1,2-vicinal diamines

Wei Pei, Cody Timmons, Xin Xu, Han Xun Wei, Guigen Li

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

α,β-Differentiated 1,2-vicinal diamines have been efficiently synthesized by using new electrophilic imidazolination reaction of alkenes. The hydrolysis of imidazolines was performed by treatment with 6 M HCl in THF at 70°C without epimerization. Eight examples were examined to give good to excellent yields (87-96%).

Original languageEnglish
Pages (from-to)2919-2921
Number of pages3
JournalOrganic and Biomolecular Chemistry
Volume1
Issue number16
DOIs
StatePublished - Aug 21 2003

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