Nickel-Catalyzed Regioselective 1,4-Hydroboration of N-Heteroarenes

Sem Raj Tamang, Arpita Singh, Daniel K. Unruh, Michael Findlater

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Combinations of Ni(acac)2 with phosphine ligands were found to catalyze the regioselective hydroboration of N-heteroarenes with pinacolborane, affording N-borylated 1,4-reduction products. Preliminary mechanistic studies have focused on the isolation and study of potential intermediates in the catalytic cycle.

Original languageEnglish
Pages (from-to)6186-6191
Number of pages6
JournalACS Catalysis
Volume8
Issue number7
DOIs
StatePublished - Jul 6 2018

Keywords

  • 1,4-regioselective
  • N-heteroarene
  • dearomatization
  • nickel
  • pyridine

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