New synthesis of Evans chiral oxazolidinones by using Sharpless AA reaction

Guigen Li; Robert Lenington; Steven Willis; Sun Hee Kim

doi:10.1039/a801404c

New synthesis of Evans chiral oxazolidinones by using Sharpless AA reaction

Guigen Li, Robert Lenington, Steven Willis, Sun Hee Kim

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Optically pure new Evans auxiliary analogs, (4R)- and (4S)-4-(2-naphthyl)oxazolidin-2-one, have been synthesized by using the Sharpless catalytic asymmetric aminohydroxylation reaction (Sharpless AA). The concise two-step synthesis involves a unique solution-to-solid Sharpless AA process and new neat cyclization conditions.

Original language	English
Pages (from-to)	1753-1754
Number of pages	2
Journal	Journal of the Chemical Society - Perkin Transactions 1
Issue number	11
DOIs	https://doi.org/10.1039/a801404c
State	Published - Jun 7 1998

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@article{85ed20583c4740c98de7afe221a9884a,

title = "New synthesis of Evans chiral oxazolidinones by using Sharpless AA reaction",

abstract = "Optically pure new Evans auxiliary analogs, (4R)- and (4S)-4-(2-naphthyl)oxazolidin-2-one, have been synthesized by using the Sharpless catalytic asymmetric aminohydroxylation reaction (Sharpless AA). The concise two-step synthesis involves a unique solution-to-solid Sharpless AA process and new neat cyclization conditions.",

author = "Guigen Li and Robert Lenington and Steven Willis and Kim, {Sun Hee}",

year = "1998",

month = jun,

day = "7",

doi = "10.1039/a801404c",

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journal = "Journal of the Chemical Society - Perkin Transactions 1",

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T1 - New synthesis of Evans chiral oxazolidinones by using Sharpless AA reaction

AU - Li, Guigen

AU - Lenington, Robert

AU - Willis, Steven

AU - Kim, Sun Hee

PY - 1998/6/7

Y1 - 1998/6/7

N2 - Optically pure new Evans auxiliary analogs, (4R)- and (4S)-4-(2-naphthyl)oxazolidin-2-one, have been synthesized by using the Sharpless catalytic asymmetric aminohydroxylation reaction (Sharpless AA). The concise two-step synthesis involves a unique solution-to-solid Sharpless AA process and new neat cyclization conditions.

AB - Optically pure new Evans auxiliary analogs, (4R)- and (4S)-4-(2-naphthyl)oxazolidin-2-one, have been synthesized by using the Sharpless catalytic asymmetric aminohydroxylation reaction (Sharpless AA). The concise two-step synthesis involves a unique solution-to-solid Sharpless AA process and new neat cyclization conditions.

UR - http://www.scopus.com/inward/record.url?scp=33748614120&partnerID=8YFLogxK

U2 - 10.1039/a801404c

DO - 10.1039/a801404c

M3 - Article

AN - SCOPUS:33748614120

SP - 1753

EP - 1754

JO - Journal of the Chemical Society - Perkin Transactions 1

JF - Journal of the Chemical Society - Perkin Transactions 1

SN - 0300-922X

IS - 11

ER -

New synthesis of Evans chiral oxazolidinones by using Sharpless AA reaction

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