New cytotoxic constituents from the Red Sea soft coral Nephthea sp.

Mohamed-Elamir F Hegazy; Amira M Gamal-Eldeen; Tarik A Mohamed; Montaser A Alhammady; Abuzeid A Hassanien; Mohamed A Shreadah; Ibrahim I Abdelgawad; Eman M Elkady; Paul Pare

New cytotoxic constituents from the Red Sea soft coral Nephthea sp.

Mohamed-Elamir F Hegazy, Amira M Gamal-Eldeen, Tarik A Mohamed, Montaser A Alhammady, Abuzeid A Hassanien, Mohamed A Shreadah, Ibrahim I Abdelgawad, Eman M Elkady, Paul Pare

Research output: Contribution to journal › Article › peer-review

Abstract

Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2–9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.

Original language	English
Pages (from-to)	1-7
Journal	Natural Product Research
State	Published - 2015

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title = "New cytotoxic constituents from the Red Sea soft coral Nephthea sp.",

abstract = "Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2–9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.",

author = "Hegazy, {Mohamed-Elamir F} and Gamal-Eldeen, {Amira M} and Mohamed, {Tarik A} and Alhammady, {Montaser A} and Hassanien, {Abuzeid A} and Shreadah, {Mohamed A} and Abdelgawad, {Ibrahim I} and Elkady, {Eman M} and Paul Pare",

year = "2015",

language = "English",

pages = "1--7",

journal = "Natural Product Research",

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TY - JOUR

T1 - New cytotoxic constituents from the Red Sea soft coral Nephthea sp.

AU - Hegazy, Mohamed-Elamir F

AU - Gamal-Eldeen, Amira M

AU - Mohamed, Tarik A

AU - Alhammady, Montaser A

AU - Hassanien, Abuzeid A

AU - Shreadah, Mohamed A

AU - Abdelgawad, Ibrahim I

AU - Elkady, Eman M

AU - Pare, Paul

PY - 2015

Y1 - 2015

N2 - Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2–9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.

AB - Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2–9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.

M3 - Article

SP - 1

EP - 7

JO - Natural Product Research

JF - Natural Product Research

ER -