TY - JOUR
T1 - New cytotoxic constituents from the Red Sea soft coral Nephthea sp.
AU - Hegazy, Mohamed-Elamir F
AU - Gamal-Eldeen, Amira M
AU - Mohamed, Tarik A
AU - Alhammady, Montaser A
AU - Hassanien, Abuzeid A
AU - Shreadah, Mohamed A
AU - Abdelgawad, Ibrahim I
AU - Elkady, Eman M
AU - Pare, Paul
PY - 2015
Y1 - 2015
N2 - Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2–9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.
AB - Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2–9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.
M3 - Article
SP - 1
EP - 7
JO - Natural Product Research
JF - Natural Product Research
ER -