New cytotoxic constituents from the Red Sea soft coral Nephthea sp.

Mohamed-Elamir F Hegazy, Amira M Gamal-Eldeen, Tarik A Mohamed, Montaser A Alhammady, Abuzeid A Hassanien, Mohamed A Shreadah, Ibrahim I Abdelgawad, Eman M Elkady, Paul Pare

Research output: Contribution to journalArticlepeer-review

Abstract

Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2–9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.
Original languageEnglish
Pages (from-to)1-7
JournalNatural Product Research
StatePublished - 2015

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