TY - JOUR
T1 - N-Phosphonyl/phosphinyl imines and group-assisted purification (GAP) chemistry/technology
AU - An, Guanghui
AU - Seifert, Cole
AU - Li, Guigen
N1 - Publisher Copyright:
© The Royal Society of Chemistry 2015.
PY - 2015/2/14
Y1 - 2015/2/14
N2 - The development of environmentally benign, operationally simple, and economically viable synthetic methodologies has been a great challenge in organic synthesis. Group-assisted purification (GAP) chemistry was established to enable the synthesis of organic compounds without using traditional purification technologies, such as column chromatography and recrystallization. This concept/technology should encourage the synthetic community to make more efforts on searching for environmentally benign reagents and reactions to reduce the waste generated from silica and solvents, particularly toxic solvents; also, to reduce production/synthesis expenses, manpower, and energy. This review will discuss the GAP concept/technology and related reactions that were mainly conducted in the PI's laboratories after 2010.
AB - The development of environmentally benign, operationally simple, and economically viable synthetic methodologies has been a great challenge in organic synthesis. Group-assisted purification (GAP) chemistry was established to enable the synthesis of organic compounds without using traditional purification technologies, such as column chromatography and recrystallization. This concept/technology should encourage the synthetic community to make more efforts on searching for environmentally benign reagents and reactions to reduce the waste generated from silica and solvents, particularly toxic solvents; also, to reduce production/synthesis expenses, manpower, and energy. This review will discuss the GAP concept/technology and related reactions that were mainly conducted in the PI's laboratories after 2010.
UR - http://www.scopus.com/inward/record.url?scp=84921963794&partnerID=8YFLogxK
U2 - 10.1039/c4ob02254h
DO - 10.1039/c4ob02254h
M3 - Article
C2 - 25523061
AN - SCOPUS:84921963794
VL - 13
SP - 1600
EP - 1617
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 6
ER -