N-linked oligosaccharides of vomeromodulin, a putative pheromone transporter in rat

Yehia Mechref, Weidong Ma, Gang Hao, Milos V. Novotny

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Vomeromodulin, a putative pheromone transporter of the rat vomeronasal organ, was isolated by lectin chromatography, purified, and subjected to a mass spectrometric (MS) system of glycan structural determination. Through a combination of exoglycosidase treatments and measurements by matrix-assisted laser desorption/ionization MS, the N-glycans of vomeromodulin were identified as mainly sialylated and fucosylated biantennary structures. The microheterogeneity of N-glycan structures was also due to the presence of galactose residues with different types of linkages.

Original languageEnglish
Pages (from-to)451-455
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume255
Issue number2
DOIs
StatePublished - Feb 16 1999

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