Monosaccharide compositional analysis of glycoproteins and glycolipids: Utility in the diagnosis/prognosis of diseases

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Different analytical methods have been developed to effectively and accurately determine monosaccharide composition of glycoproteins and glycolipids in biological and biomedical samples. These methods included high-performance anion-exchange chromatography with pulse amperometric detection (HPAEC-PAD), high-performance liquid chromatography with fluorescence detection (HPLC-FL), and capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). This chapter reviews the development of these methods, and evaluates their potential application in the diagnosis or prognosis of diseases.

Original languageEnglish
Title of host publicationCapillary Electrophoresis of Carbohydrates
Subtitle of host publicationFrom Monosaccharides to Complex Polysaccharides
PublisherHumana Press Inc.
Pages237-267
Number of pages31
ISBN (Electronic)9781607618751
ISBN (Print)9781607618744
DOIs
StatePublished - 2011

Keywords

  • Capillary electrophoresis
  • Diagnosis
  • Glycolipids
  • Glycoproteins
  • HPAEC-PAD
  • HPLC-FL
  • HPLC-MS
  • Laser-induced fluorescence
  • Monosaccharides
  • Oligosaccharides
  • Prognosis

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  • Cite this

    Mechref, Y. (2011). Monosaccharide compositional analysis of glycoproteins and glycolipids: Utility in the diagnosis/prognosis of diseases. In Capillary Electrophoresis of Carbohydrates: From Monosaccharides to Complex Polysaccharides (pp. 237-267). Humana Press Inc.. https://doi.org/10.1007/978-1-60761-875-1_10