Monoamines and their metabolites in the amphibian (Ambystoma tigrinum) brain: Quantitative changes during metamorphosis and captivity

David O. Norris, James A. Carr, Paul H. Desan, Tim K. Smock, Mark F. Norman

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

1. 1. Monoamine neurotransmitters (epinephrine, norepinephrine, dopamine, serotonin and some of their metabolites (DOPEG, MHPG, DOPAC, 5-HIAA) were measured by HPLC in extracts from telencephalon (TEL) and diencephalon-midbrain (DM) before, during and at the end of metamorphosis. 2. 2. During metamorphosis MHPG increased and 5-HIAA decreased in TEL and DM while DOPEG decreased only in DM. 3. 3. Monoamine levels were greater in the TEL and a larger increase in MHPG occurred there. 4. 4. Captivity without metamorphosis also caused a significant depression of 5-HIAA in TEL and depression of DOPEG, MHPG and DOPAC in DM.

Original languageEnglish
Pages (from-to)279-283
Number of pages5
JournalComparative Biochemistry and Physiology -- Part A: Physiology
Volume103
Issue number2
DOIs
StatePublished - Oct 1992

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