TY - JOUR
T1 - Monoamines and their metabolites in the amphibian (Ambystoma tigrinum) brain
T2 - Quantitative changes during metamorphosis and captivity
AU - Norris, David O.
AU - Carr, James A.
AU - Desan, Paul H.
AU - Smock, Tim K.
AU - Norman, Mark F.
N1 - Funding Information:
Acknowledgements-The authorsw ith to thankD r Richard E. Jones for numerous discussionsa nd for reviewing this manuscript. Dr William A. Gern kindly supplied the animals.T his work was supportedi n part by a BRSG Grant RR07013-198a6w ardedb y the BiomedicaRl esearch Support Grant Program,D ivision of ResearchR esources, National Instituteso f Health.
PY - 1992/10
Y1 - 1992/10
N2 - 1. 1. Monoamine neurotransmitters (epinephrine, norepinephrine, dopamine, serotonin and some of their metabolites (DOPEG, MHPG, DOPAC, 5-HIAA) were measured by HPLC in extracts from telencephalon (TEL) and diencephalon-midbrain (DM) before, during and at the end of metamorphosis. 2. 2. During metamorphosis MHPG increased and 5-HIAA decreased in TEL and DM while DOPEG decreased only in DM. 3. 3. Monoamine levels were greater in the TEL and a larger increase in MHPG occurred there. 4. 4. Captivity without metamorphosis also caused a significant depression of 5-HIAA in TEL and depression of DOPEG, MHPG and DOPAC in DM.
AB - 1. 1. Monoamine neurotransmitters (epinephrine, norepinephrine, dopamine, serotonin and some of their metabolites (DOPEG, MHPG, DOPAC, 5-HIAA) were measured by HPLC in extracts from telencephalon (TEL) and diencephalon-midbrain (DM) before, during and at the end of metamorphosis. 2. 2. During metamorphosis MHPG increased and 5-HIAA decreased in TEL and DM while DOPEG decreased only in DM. 3. 3. Monoamine levels were greater in the TEL and a larger increase in MHPG occurred there. 4. 4. Captivity without metamorphosis also caused a significant depression of 5-HIAA in TEL and depression of DOPEG, MHPG and DOPAC in DM.
UR - http://www.scopus.com/inward/record.url?scp=0026786358&partnerID=8YFLogxK
U2 - 10.1016/0300-9629(92)90580-J
DO - 10.1016/0300-9629(92)90580-J
M3 - Article
C2 - 1359951
AN - SCOPUS:0026786358
SN - 0300-9629
VL - 103
SP - 279
EP - 283
JO - Comparative Biochemistry and Physiology -- Part A: Physiology
JF - Comparative Biochemistry and Physiology -- Part A: Physiology
IS - 2
ER -