Molecular Architecture and Biomedical Leads of Terpenes from Red Sea Marine Invertebrates

Mohamed Elamir F Hegazy, Tarik A Mohamed, Montaser A Alhammady, Alaa M Shaheen, Eman H Reda, Abdelsamed I Elshamy, Mina Aziz, Paul Pare

Research output: Contribution to journalArticlepeer-review


Marine invertebrates including sponges, soft coral, tunicates, mollusks and bryozoan have proved to be a prolific source of bioactive natural products. Among marine-derived metabolites, terpenoids have provided a vast array of molecular architectures. These isoprenoid-derived metabolites also exhibit highly specialized biological activities ranging from nerve regeneration to blood-sugar regulation. As a result, intense research activity has been devoted to characterizing invertebrate terpenes from both a chemical and biological standpoint. This review focuses on the chemistry and biology of terpene metabolites isolated from the Red Sea ecosystem, a unique marine biome with one of the highest levels of biodiversity and specifically rich in invertebrate species.
Original languageEnglish
Pages (from-to)3154-3181
JournalMarine Drugs
StatePublished - 2015


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