Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics

Hermann B. Frieboes; Kenji Yokoi; Bhuvanesh Dave; Fazle Hussain; Biana Godin

doi:10.4032/9789814364423

Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics

Hermann B. Frieboes, Kenji Yokoi, Bhuvanesh Dave, Fazle Hussain, Biana Godin

Mechanical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

In this chapter, we review literature emphasizing the importance of bio-barriers in the tumor microenvironment and the main modeling approaches to predict transport of therapeutics across these obstacles. We further describe design considerations of the nanovectors to overcome the biobarriers.

Original language	English
Title of host publication	Mass Transport of Nanocarriers
Publisher	Pan Stanford Publishing Pte. Ltd.
Pages	137-183
Number of pages	47
ISBN (Print)	9789814364416
DOIs	https://doi.org/10.4032/9789814364423
State	Published - Dec 31 2012

Access to Document

10.4032/9789814364423

Cite this

@inbook{d19c27bfabfb4c3fb7a5bf43356fe1d6,

title = "Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics",

abstract = "In this chapter, we review literature emphasizing the importance of bio-barriers in the tumor microenvironment and the main modeling approaches to predict transport of therapeutics across these obstacles. We further describe design considerations of the nanovectors to overcome the biobarriers.",

author = "Frieboes, {Hermann B.} and Kenji Yokoi and Bhuvanesh Dave and Fazle Hussain and Biana Godin",

year = "2012",

month = dec,

day = "31",

doi = "10.4032/9789814364423",

language = "English",

isbn = "9789814364416",

pages = "137--183",

booktitle = "Mass Transport of Nanocarriers",

publisher = "Pan Stanford Publishing Pte. Ltd.",

}

TY - CHAP

T1 - Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics

AU - Frieboes, Hermann B.

AU - Yokoi, Kenji

AU - Dave, Bhuvanesh

AU - Hussain, Fazle

AU - Godin, Biana

PY - 2012/12/31

Y1 - 2012/12/31

N2 - In this chapter, we review literature emphasizing the importance of bio-barriers in the tumor microenvironment and the main modeling approaches to predict transport of therapeutics across these obstacles. We further describe design considerations of the nanovectors to overcome the biobarriers.

AB - In this chapter, we review literature emphasizing the importance of bio-barriers in the tumor microenvironment and the main modeling approaches to predict transport of therapeutics across these obstacles. We further describe design considerations of the nanovectors to overcome the biobarriers.

UR - http://www.scopus.com/inward/record.url?scp=84881989094&partnerID=8YFLogxK

U2 - 10.4032/9789814364423

DO - 10.4032/9789814364423

M3 - Chapter

AN - SCOPUS:84881989094

SN - 9789814364416

SP - 137

EP - 183

BT - Mass Transport of Nanocarriers

PB - Pan Stanford Publishing Pte. Ltd.

ER -

Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics

Abstract

Access to Document

Other files and links

Fingerprint

Cite this