Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics

Hermann B. Frieboes, Kenji Yokoi, Bhuvanesh Dave, Fazle Hussain, Biana Godin

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

In this chapter, we review literature emphasizing the importance of bio-barriers in the tumor microenvironment and the main modeling approaches to predict transport of therapeutics across these obstacles. We further describe design considerations of the nanovectors to overcome the biobarriers.

Original languageEnglish
Title of host publicationMass Transport of Nanocarriers
PublisherPan Stanford Publishing Pte. Ltd.
Pages137-183
Number of pages47
ISBN (Print)9789814364416
DOIs
StatePublished - Dec 31 2012

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