Mitigating aflatoxin contamination in groundnut through a combination of genetic resistance and post-harvest management practices

Manish K. Pandey, Rakesh Kumar, Arun K. Pandey, Pooja Soni, Sunil S. Gangurde, Hari K. Sudini, Jake C. Fountain, Boshou Liao, Haile Desmae, Patrick Okori, Xiaoping Chen, Huifang Jiang, Venugopal Mendu, Hamidou Falalou, Samuel Njoroge, James Mwololo, Baozhu Guo, Weijian Zhuang, Xingjun Wang, Xuanqiang LiangRajeev K. Varshney

Research output: Contribution to journalReview article

13 Scopus citations

Abstract

Aflatoxin is considered a “hidden poison” due to its slow and adverse effect on various biological pathways in humans, particularly among children, in whom it leads to delayed development, stunted growth, liver damage, and liver cancer. Unfortunately, the unpredictable behavior of the fungus as well as climatic conditions pose serious challenges in precise phenotyping, genetic prediction and genetic improvement, leaving the complete onus of preventing aflatoxin contamination in crops on post-harvest management. Equipping popular crop varieties with genetic resistance to aflatoxin is key to effective lowering of infection in farmer’s fields. A combination of genetic resistance for in vitro seed colonization (IVSC), pre-harvest aflatoxin contamination (PAC) and aflatoxin production together with pre- and post-harvest management may provide a sustainable solution to aflatoxin contamination. In this context, modern “omics” approaches, including next-generation genomics technologies, can provide improved and decisive information and genetic solutions. Preventing contamination will not only drastically boost the consumption and trade of the crops and products across nations/regions, but more importantly, stave off deleterious health problems among consumers across the globe.

Original languageEnglish
Article number315
JournalToxins
Volume11
Issue number6
DOIs
StatePublished - Jun 2019

Keywords

  • Aflatoxin contamination
  • Aspergillus flavus
  • Genetic resistance
  • Groundnut
  • Post-harvest management

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    Pandey, M. K., Kumar, R., Pandey, A. K., Soni, P., Gangurde, S. S., Sudini, H. K., Fountain, J. C., Liao, B., Desmae, H., Okori, P., Chen, X., Jiang, H., Mendu, V., Falalou, H., Njoroge, S., Mwololo, J., Guo, B., Zhuang, W., Wang, X., ... Varshney, R. K. (2019). Mitigating aflatoxin contamination in groundnut through a combination of genetic resistance and post-harvest management practices. Toxins, 11(6), [315]. https://doi.org/10.3390/toxins11060315