TY - JOUR
T1 - Metal-free preparation of cycloalkyl aryl sulfides via di-tert-butyl peroxide-promoted oxidative C(sp3)-H bond thiolation of cycloalkanes
AU - Zhao, Jincan
AU - Fang, Hong
AU - Han, Jianlin
AU - Pan, Yi
AU - Li, Guigen
PY - 2014/8/11
Y1 - 2014/8/11
N2 - A concise thiolation of the C(sp3)-H bond of cycloalkanes with diaryl disulfides in the presence of the oxidant di-tert-butyl peroxide (DTBP) has been developed. This reaction, without using any metal catalyst, tolerates varieties of disulfides and cycloalkanes substrates, giving good to excellent chemical yields, and thus provides a useful approach to cycloalkyl aryl sulfides from unactivated cycloalkanes.
AB - A concise thiolation of the C(sp3)-H bond of cycloalkanes with diaryl disulfides in the presence of the oxidant di-tert-butyl peroxide (DTBP) has been developed. This reaction, without using any metal catalyst, tolerates varieties of disulfides and cycloalkanes substrates, giving good to excellent chemical yields, and thus provides a useful approach to cycloalkyl aryl sulfides from unactivated cycloalkanes.
KW - cycloalkanes
KW - metal-free conditions
KW - oxidative process
KW - thiolation
UR - http://www.scopus.com/inward/record.url?scp=84906231572&partnerID=8YFLogxK
U2 - 10.1002/adsc.201400032
DO - 10.1002/adsc.201400032
M3 - Article
AN - SCOPUS:84906231572
SN - 1615-4150
VL - 356
SP - 2719
EP - 2724
JO - Advanced Synthesis and Catalysis
JF - Advanced Synthesis and Catalysis
IS - 11-12
ER -