Metabolism of mevalonic acid to long chain fatty alcohols in an insect

W. David Nes, Bruce C. Campbell, Allan E. Stafford, William F. Haddon, Mabry Benson

Research output: Contribution to journalArticlepeer-review

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A mixture of long chain fatty alcohols (LCFA) with chain lengths of 24 to 30 carbon atoms, as free and esterified components, have been isolated from the aphid, Schizaphis graminum. Both radiolabelled mevalonic acid and palmitic acid served as effective precursors in the synthesis of LCFA. This is the first time that the trans-methylglutaconate shunt has been shown to be operational for fatty alcohol synthesis and to occur in a lower-evolved animal.

Original languageEnglish
Pages (from-to)1258-1263
Number of pages6
JournalBiochemical and Biophysical Research Communications
Issue number3
StatePublished - Oct 15 1982


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