Mechanism and structural requirements for transformation of substrates by the (S)-adenosyl-L-methionine:Δ²⁴⁽²⁵⁾sterol methyl transferase from Saccharomyces cerevisiae

Medicine & Life Sciences

• S-Adenosylmethionine 91%
• Sterols 81%
• Transferases 71%
• Saccharomyces cerevisiae 64%
• zymosterol 11%
• Deuterium 8%
• Catalysis 6%
• Homocysteine 6%
• Isotopes 6%
• Protons 5%
• Catalytic Domain 5%
• Enzymes 3%

Chemistry

• S-Adenosyl-L-Methionine 100%
• Sterol 76%
• Chemical Transformation 43%
• Zymosterol 11%
• S-Adenosyl-L-Homocysteine 10%
• Isotope Effect 6%
• Deuterium(.) 5%
• Methyl Group 5%
• Velocity 5%
• Strain 4%
• Proton 4%
• Catalysis 4%
• Energy 2%
• Mixture 2%
• Molecule 2%