Manoyl oxide α-arabinopyranoside and grindelic acid diterpenoids from Grindelia integrifolia

A. A. Ahmed, A. A. Mahmoud, U. M. Ahmed, A. A. El-Bassuony, M. H. Abd El-Razk, P. W. Pare, J. Karchesy

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Two new manoyl oxide-α-arabinopyranoside diterpenoids, 15-hydroxy-13-epi-manoyl oxide-14-O-α-L-arabinopyranoside (tarapacol-14-O-α-L-arabinopyranoside) (1) and 15-acetoxy-13-epi-manoyl oxide-14-O-α-L-arabinopyranoside (tarapacol-15-acetate-14-O-α-L-arabinopyranoside) (2), as well as a new grindelic acid derivative, 19-hydroxygrindelic acid (3), together with five known diterpenoids (tarapacol, tarapacanol A, grindelic acid, methyl grindeloate, 3β-hydroxygrindelic acid, 4) were isolated from the aerial parts of Grindelia integrifolia. The structures of 1-3 were elucidated by spectral data analysis.

Original languageEnglish
Pages (from-to)1365-1367
Number of pages3
JournalJournal of Natural Products
Volume64
Issue number10
DOIs
StatePublished - 2001

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