L-Theanine and caffeine improve target-specific attention to visual stimuli by decreasing mind wandering: a human functional magnetic resonance imaging study.

Chanaka N Kahathuduwa, Samundini Dhanasekara, Shao-Hua Chin, T Davis, T L Dassanayake, V S Weerasinghe, T L Dassanayake, Martin Binks

Research output: Contribution to journalArticlepeer-review

Abstract

Oral intake of l-theanine and caffeine supplements is known to be associated with faster stimulus discrimination, possibly via improving attention to stimuli. We hypothesized that l-theanine and caffeine may be bringing about this beneficial effect by increasing attention-related neural resource allocation to target stimuli and decreasing deviation of neural resources to distractors. We used functional magnetic resonance imaging (fMRI) to test this hypothesis. Solutions of 200 mg of l-theanine, 160 mg of caffeine, their combination, or the vehicle (distilled water; placebo) were administered in a randomized 4-way crossover design to 9 healthy adult men. Sixty minutes after administration, a 20-minute fMRI scan was performed while the subjects performed a visual color stimulus discrimination task. l-Theanine and l-theanine–caffeine combination resulted in faster responses to targets compared with placebo (∆ = 27.8 milliseconds, P = .018 and ∆ = 26.7 milliseconds, P = .037, respectively
Original languageEnglish
Pages (from-to)67-78
JournalNutrition Research / Elsevier
DOIs
StatePublished - Jan 2018

Fingerprint

Dive into the research topics of 'L-Theanine and caffeine improve target-specific attention to visual stimuli by decreasing mind wandering: a human functional magnetic resonance imaging study.'. Together they form a unique fingerprint.

Cite this