L-Citrulline supports vascular and muscular benefits of exercise training in older adults

Arturo Figueroa, Salvador J. Jaime, Masahiko Morita, Joaquin U. Gonzales, Christophe Moinard

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Age-associated reduction in endothelial nitric oxide (NO) synthesis contributes to the development of cardiovascular diseases and sarcopenia. l-Citrulline is a precursor of NO with the ability to improve vascular function and muscle protein synthesis. We hypothesize that vascular and muscular benefits associated with oral l-citrulline supplementation might be augmented by concomitant supplementation with exercise training in older adults.

Original languageEnglish
Pages (from-to)133-139
Number of pages7
JournalExercise and Sport Sciences Reviews
Volume48
Issue number3
DOIs
StatePublished - Jul 1 2020

Keywords

  • arterial aging
  • exercise performance
  • muscle protein synthesis
  • nitric oxide
  • oral l -citrulline
  • sarcopenia
  • vascular dysfunction

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