Abstract
Age-associated reduction in endothelial nitric oxide (NO) synthesis contributes to the development of cardiovascular diseases and sarcopenia. l-Citrulline is a precursor of NO with the ability to improve vascular function and muscle protein synthesis. We hypothesize that vascular and muscular benefits associated with oral l-citrulline supplementation might be augmented by concomitant supplementation with exercise training in older adults.
Original language | English |
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Pages (from-to) | 133-139 |
Number of pages | 7 |
Journal | Exercise and Sport Sciences Reviews |
Volume | 48 |
Issue number | 3 |
DOIs | |
State | Published - Jul 1 2020 |
Keywords
- arterial aging
- exercise performance
- muscle protein synthesis
- nitric oxide
- oral l -citrulline
- sarcopenia
- vascular dysfunction