Key Considerations for Accurate Exposures in Ecotoxicological Assessments of Perfluorinated Carboxylates and Sulfonates

Justin N. Rewerts; Emerson C. Christie; Alix E. Robel; Todd A. Anderson; Christopher McCarthy; Christopher J. Salice; Jennifer A. Field

doi:10.1002/etc.4667

Key Considerations for Accurate Exposures in Ecotoxicological Assessments of Perfluorinated Carboxylates and Sulfonates

Justin N. Rewerts, Emerson C. Christie, Alix E. Robel, Todd A. Anderson, Christopher McCarthy, Christopher J. Salice, Jennifer A. Field

Environmental Toxicology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Toxicity reference values for per- and polyfluoroalkyl substances (PFAS) vary even when the same test organism is studied. Although the need to confirm dosing solution concentrations is widely accepted, there are no experimental data to inform best practices when PFAS solutions are prepared. Laboratory data indicate that dissolution time of PFAS solids causes statistically significant deviations between nominal and measured concentrations. Mixing times for select PFAS varied between 2 and 5 h, depending on carbon fluorine chain-length. Environ Toxicol Chem 2020;00:1–12.

Original language	English
Journal	Environmental Toxicology and Chemistry
DOIs	https://doi.org/10.1002/etc.4667
State	Accepted/In press - 2020

Keywords

Dosing
Ecotoxicology
Exposure
Per- and polyfluoroalkyl substances
Variability

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10.1002/etc.4667

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abstract = "Toxicity reference values for per- and polyfluoroalkyl substances (PFAS) vary even when the same test organism is studied. Although the need to confirm dosing solution concentrations is widely accepted, there are no experimental data to inform best practices when PFAS solutions are prepared. Laboratory data indicate that dissolution time of PFAS solids causes statistically significant deviations between nominal and measured concentrations. Mixing times for select PFAS varied between 2 and 5 h, depending on carbon fluorine chain-length. Environ Toxicol Chem 2020;00:1–12.",

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Key Considerations for Accurate Exposures in Ecotoxicological Assessments of Perfluorinated Carboxylates and Sulfonates. / Rewerts, Justin N.; Christie, Emerson C.; Robel, Alix E.; Anderson, Todd A.; McCarthy, Christopher; Salice, Christopher J.; Field, Jennifer A.

In: Environmental Toxicology and Chemistry, 2020.

Research output: Contribution to journal › Article › peer-review

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T1 - Key Considerations for Accurate Exposures in Ecotoxicological Assessments of Perfluorinated Carboxylates and Sulfonates

AU - Rewerts, Justin N.

AU - Christie, Emerson C.

AU - Robel, Alix E.

AU - Anderson, Todd A.

AU - McCarthy, Christopher

AU - Salice, Christopher J.

AU - Field, Jennifer A.

PY - 2020

Y1 - 2020

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KW - Dosing

KW - Ecotoxicology

KW - Exposure

KW - Per- and polyfluoroalkyl substances

KW - Variability

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