Key Considerations for Accurate Exposures in Ecotoxicological Assessments of Perfluorinated Carboxylates and Sulfonates

Justin N. Rewerts, Emerson C. Christie, Alix E. Robel, Todd A. Anderson, Christopher McCarthy, Christopher J. Salice, Jennifer A. Field

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Toxicity reference values for per- and polyfluoroalkyl substances (PFAS) vary even when the same test organism is studied. Although the need to confirm dosing solution concentrations is widely accepted, there are no experimental data to inform best practices when PFAS solutions are prepared. Laboratory data indicate that dissolution time of PFAS solids causes statistically significant deviations between nominal and measured concentrations. Mixing times for select PFAS varied between 2 and 5 h, depending on carbon fluorine chain-length. Environ Toxicol Chem 2021;40:677–688.

Original languageEnglish
Pages (from-to)677-688
Number of pages12
JournalEnvironmental Toxicology and Chemistry
Volume40
Issue number3
DOIs
StatePublished - Mar 2021

Keywords

  • Dosing
  • Ecotoxicology
  • Exposure
  • Per- and polyfluoroalkyl substances
  • Variability

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