TY - JOUR
T1 - Ketoisophorone transformation by Marchantia polymorpha and Nicotiana tabacum cultured cells
AU - Hegazy, Mohamed Elamir F.
AU - Hirata, Toshifumi
AU - Abdel-Lateff, Ahmed
AU - Abd El-Razek, Mohamed H.
AU - Mohamed, Abou El Hamd H.
AU - Hassan, Nahed M.
AU - Paré, Paul W.
AU - Mahmoud, Ahmed A.
N1 - Funding Information:
Financial assistance was provided in part by the Robert Welch Foundation (D1478).
PY - 2008
Y1 - 2008
N2 - Stereospecific olefin (C=C) and carbonyl (C=O) reduction of the readily available prochiral compound ketoisophorone (2,2,6-trimethyl-2-cyclohexene-1,4- dione) (1) by Marchantia polymorpha and Nicotiana tabacum cell suspension cultures produce the chiral products (6R)-levodione (2), (4R,5S)-4-hydroxy-3,3, 5-trimethylcyclohexanone (3), and (4R,6R)-actinol (4) as well as the minor components (4R)-hydroxyisophorone (5) and (4S)-phorenol (6).
AB - Stereospecific olefin (C=C) and carbonyl (C=O) reduction of the readily available prochiral compound ketoisophorone (2,2,6-trimethyl-2-cyclohexene-1,4- dione) (1) by Marchantia polymorpha and Nicotiana tabacum cell suspension cultures produce the chiral products (6R)-levodione (2), (4R,5S)-4-hydroxy-3,3, 5-trimethylcyclohexanone (3), and (4R,6R)-actinol (4) as well as the minor components (4R)-hydroxyisophorone (5) and (4S)-phorenol (6).
KW - Cultured plant cells
KW - Hydrogenation
KW - Ketoisophorone
UR - http://www.scopus.com/inward/record.url?scp=48249137365&partnerID=8YFLogxK
U2 - 10.1515/znc-2008-5-615
DO - 10.1515/znc-2008-5-615
M3 - Article
C2 - 18669027
AN - SCOPUS:48249137365
SN - 0939-5075
VL - 63
SP - 403
EP - 408
JO - Zeitschrift fur Naturforschung - Section C Journal of Biosciences
JF - Zeitschrift fur Naturforschung - Section C Journal of Biosciences
IS - 5-6
ER -