Jun protein function in myogenesis

Basak Icli, Curtis Pfarr, Theodore Wiesner

Research output: Contribution to journalConference articlepeer-review


The CL26 cell line was used to establish the role of AP-1 activity. The time course of c-Jun, JunB and JunD during the differentiation of C2C12 (control) and CL26 cell line myoblasts were monitored. Both the control and engineered cell lines were induced to differentiate by reducing serum concentration. Results support the hypothesis that decreased AP-1 activity is a sufficient condition for the onset of differentiation.

Original languageEnglish
Pages (from-to)S-7
JournalAnnals of Biomedical Engineering
Issue numberSUPPL. 1
StatePublished - 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000


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