Iron Catalyzed Hydroboration of Aldehydes and Ketones

Sem Raj Tamang, Michael Findlater

Research output: Contribution to journalArticle

55 Scopus citations

Abstract

We report an operationally convenient room temperature hydroboration of aldehydes and ketones employing Fe(acac)3 as precatalyst. The hydroboration of aldehydes and ketones proceeded efficiently at room temperature to yield, after work up, 1° and 2° alcohols; chemoselective hydroboration of aldehydes over ketones is attained under these conditions. We propose a σ-bond metathesis mechanism in which an Fe-H intermediate is postulated to be a key reactive species.

Original languageEnglish
Pages (from-to)12857-12862
Number of pages6
JournalJournal of Organic Chemistry
Volume82
Issue number23
DOIs
StatePublished - Dec 1 2017

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