Identification of ergosta-6(7),8(14),25(27)-trien-3β-ol and ergosta-5(6),7(8),25(27)-trien-3β-ol, two new steroidal trienes synthesized by Prototheca wickerhamii

Robert A. Norton, W. David Nes

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Ergosta-6(7),8(14),25(27)-trien-3β-ol, ergosta-5(6),7(8),25(27)-trien-3β-ol, ergosterol, 25(27)-dehydroergosterol (protothecasterol), ergosta-7,25(27)-dien-3β-ol and ergost-7-en-3β-ol have been isolated from cells of Prototheca wickerhamii. The structures of the compounds have been determined in stereochemical detail by a series of chromatographic and spectral techniques. The results are interpreted to imply that whereas P. wickerhamii is non-photosynthetic and yeast-like in appearance and synthesizes ergosterol, the organism can be biochemically distinguished from yeast and considered an alga in part through the detection of other sterols described herein, notably those with Δ25(27) side chains.

Original languageEnglish
Pages (from-to)247-249
Number of pages3
JournalLipids
Volume26
Issue number3
DOIs
StatePublished - Mar 1991

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