TY - JOUR
T1 - Hypertension and Hyperthyroidism
T2 - Association and Pathogenesis
AU - Rivas, Ana M.
AU - Pena, Camilo
AU - Kopel, Jonathan
AU - Dennis, Jeff A.
AU - Nugent, Kenneth
N1 - Publisher Copyright:
© 2020
PY - 2021/1
Y1 - 2021/1
N2 - Hypertension can cause significant morbidity and reduced life expectancy. Most patients with hypertension have primary hypertension; however, 10 to 15% of patients have secondary hypertension. Endocrine disorders explain approximately 10% of hypertension in all patients, and thyroid disorders account for approximately 1% of cases with hypertension. Hyperthyroidism can cause increased cardiac output, increased systolic blood pressures, and increased levels of renin, angiotensin, and aldosterone. Treatment of hyperthyroidism can cure hypertension in some patients. Consequently, identification of patients with secondary hypertension potentially has important benefits, and understanding secondary hypertension provides a framework for investigating the pathophysiology of hypertension. Clinicians should consider the possibility of hyperthyroidism in patients with hypertension, even in those of more advanced age.
AB - Hypertension can cause significant morbidity and reduced life expectancy. Most patients with hypertension have primary hypertension; however, 10 to 15% of patients have secondary hypertension. Endocrine disorders explain approximately 10% of hypertension in all patients, and thyroid disorders account for approximately 1% of cases with hypertension. Hyperthyroidism can cause increased cardiac output, increased systolic blood pressures, and increased levels of renin, angiotensin, and aldosterone. Treatment of hyperthyroidism can cure hypertension in some patients. Consequently, identification of patients with secondary hypertension potentially has important benefits, and understanding secondary hypertension provides a framework for investigating the pathophysiology of hypertension. Clinicians should consider the possibility of hyperthyroidism in patients with hypertension, even in those of more advanced age.
KW - Epidemiology
KW - Hypertension
KW - Hyperthyroidism
KW - Pathophysiology
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=85092012215&partnerID=8YFLogxK
U2 - 10.1016/j.amjms.2020.08.012
DO - 10.1016/j.amjms.2020.08.012
M3 - Review article
C2 - 33012487
AN - SCOPUS:85092012215
SN - 0002-9629
VL - 361
SP - 3
EP - 7
JO - American Journal of the Medical Sciences
JF - American Journal of the Medical Sciences
IS - 1
ER -