A dedicated small animal x-ray computed tomography system has been developed to screen mutagenized mice for anatomical phenotypes. The key components of the data acquisition instrumentation are described along with the system performance parameters. Image reconstruction, visualization and segmentation software algorithms are described. Two contrast media regimens are described and representative studies of mice with adipose, soft and skeletal tissue abnormalities are presented.
|Number of pages||10|
|Journal||Proceedings of SPIE - The International Society for Optical Engineering|
|State||Published - 2000|
|Event||Optical Diagnostics of Living Cells III - San Jose, CA, USA|
Duration: Jan 24 2000 → Jan 25 2000