Growth standards of infants with Prader-Willi syndrome

M G Butler, J Sturich, Jae Hoon Lee, S E Myers, B Y Whitman, J-A Gold, V Kimonis, A Scheimann, N Terrazas, D J Driscoll

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: To generate and report standardized growth curves for weight, length, head circumference, weight/length, and BMI for non–growth hormone–treated white infants (boys and girls) with Prader-Willi syndrome (PWS) between 0 and 36 months of age. The goal was to monitor growth and compare data with other infants with PWS. METHODS: Anthropometric measures (N = 758) were obtained according to standard methods and analyzed from 186 non–growth hormone–treated white infants (108 boys and 78 girls) with PWS between 0 and 36 months of age. Standardized growth curves were developed and the 3rd, 10th, 25th, 50th, 75th, 90th, and 97th percentiles were calculated by using the LMS (refers to λ, μ, and σ) smoothing procedure method for weight, length, head circumference, weight/length, and BMI along with the normative 50th percentile using Centers for Disease Control and Prevention national growth data from 2003. The data were plotted for comparison purposes. RESULTS: Five separate standa
Original languageEnglish
Pages (from-to)687695
JournalPediatrics
StatePublished - 2011

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