Green tea and bone health: Evidence from laboratory studies

Chwan Li Shen, James K. Yeh, Jay J. Cao, Ming Chien Chyu, Jia Sheng Wang

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Osteoporosis is a major health problem in the elderly. Epidemiological evidence has shown an association between tea consumption and the prevention of bone loss in the elderly population. Ingestion of green tea and green tea bioactive compounds may be beneficial in mitigating bone loss of this population and decreasing their risk of osteoporotic fractures. This review describes the effect of green tea with its bioactive components on bone health with an emphasis on the following: (i) the etiology of osteoporosis, (ii) evidence of osteo-protective impacts of green tea on bone mass and microarchitecture in various bone loss models in which induced by aging, sex hormone deficiency, and chronic inflammation, (iii) discussion of impacts of green tea on bone mass in two obesity models, (iv) observation of short-term green tea supplementation given to postmenopausal women with low bone mass, (v) possible mechanisms for the osteo-protective effects of green tea bioactive compounds, and (vi) a summary and future research direction of green tea and bone health.

Original languageEnglish
Pages (from-to)155-161
Number of pages7
JournalPharmacological Research
Volume64
Issue number2
DOIs
StatePublished - Aug 2011

Keywords

  • Antioxidant
  • Bone mineral density
  • Cell
  • Human
  • Osteoporosis
  • Rat
  • Tea polyphenols

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