Glycerophospholipid analysis of eastern red bat (Lasiurus borealis) hair by electrospray ionization tandem mass spectrometry

Evan L Pannkuk, Liam McGuire, David F Gilmore, Brett J Savary, Thomas S Risch

Research output: Contribution to journalArticle


Pilosebaceous units found in the mammalian integument are composed of a hair follicle, the proximal portion of the hair shaft, a sebaceous gland, and the erector pili muscle. Pilosebaceous units release protective oils, or sebum, by holocrine secretion onto skin and hair through rupturing of sebocytes. Sebum is composed largely of polar and neutral lipids including glycerolipids, free fatty acids, sterols, wax esters, sterol esters, and squalene. In addition to these lipid classes, there is a small proportion of ionic/anionic glycerophospholipids (GPs). Composition of GPs on hair is rarely addressed despite their broad biological activities as signaling molecules and membrane stability. Furthermore, knowledge on GP composition in bats is lacking. Bat GP composition is important to document due to GP roles ranging from decreasing drag during migration to interaction with the integumentary microbiome. In this study, we analyzed GP molecular composition with liquid chromatography electro
Original languageEnglish
Pages (from-to)227-235
JournalJournal of Chemical Ecology
StatePublished - Mar 2014


Cite this