Glucocorticoids, aerobic physiology, and locomotor behavior in California Mice.

Elizabeth M Dlugosz, Breanna Harris, Wendy Saltzman, Mark A Chappell

Research output: Contribution to journalArticlepeer-review


The glucocorticoid hormones corticosterone (CORT) and cortisol influence numerous physiological, morphological, and behavioral functions. However, few studies have addressed possible relationships between individual differences in glucocorticoid concentrations and whole-animal performance or metabolism. Because CORT is important in glucose regulation and energy metabolism and can influence activity levels, we hypothesized that individual variation in baseline circulating CORT levels would correlate with individual differences in energy expenditure (routine and maximal), aerobic physiology, voluntary exercise on wheels, and organ masses. We tested this hypothesis in the California mouse (Peromyscus californicus). We collected data from 54 adult, colony-bred mice on baseline CORT levels (measured near both the circadian peak and the circadian trough), voluntary wheel running and its energetic costs, maximal oxygen consumption during forced treadmill exercise ( ), basal metabolic rate, a
Original languageEnglish
Pages (from-to)671-683
JournalPhysiological and Biochemical Zoology
StatePublished - 2012


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