Geographic distribution and genetic diversity of Whitewater Arroyo virus in the southwestern United States.

C. F. Fulhorst; R. N. Charrel; S. C. Weaver; T. G. Ksiazek; R. D. Bradley; M. L. Milazzo; R. B. Tesh; M. D. Bowen

doi:10.3201/eid0703.017306

Geographic distribution and genetic diversity of Whitewater Arroyo virus in the southwestern United States.

C. F. Fulhorst, R. N. Charrel, S. C. Weaver, T. G. Ksiazek, R. D. Bradley, M. L. Milazzo, R. B. Tesh, M. D. Bowen

Biological Sciences

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

The purpose of this study was to extend our knowledge of the geographic distribution and genetic diversity of the arenavirus(es) associated with Neotoma species (woodrats) in the southwestern United States. Infectious arenavirus was recovered from 14 (3.3%) of 425 woodrats. The virus-positive species included N. albigula in New Mexico and Oklahoma, N. cinerea in Utah, N. mexicana in New Mexico and Utah, and N. micropus in Texas. Analyses of viral nucleocapsid protein gene sequence data indicated that all the isolates were strains of the Whitewater Arroyo virus, an arenavirus previously known only from northwestern New Mexico. Analyses of the sequence data also indicated that there can be substantial genetic diversity among strains of Whitewater Arroyo virus from conspecific woodrats collected from different localities and substantial genetic diversity among strains from different woodrat species collected from the same locality.

Original language	English
Pages (from-to)	403-407
Number of pages	5
Journal	Emerging infectious diseases
Volume	7
Issue number	3
DOIs	https://doi.org/10.3201/eid0703.017306
State	Published - 2001

Access to Document

10.3201/eid0703.017306

Cite this

@article{295748ec0f674ff4ae54d88e5e15a144,

title = "Geographic distribution and genetic diversity of Whitewater Arroyo virus in the southwestern United States.",

abstract = "The purpose of this study was to extend our knowledge of the geographic distribution and genetic diversity of the arenavirus(es) associated with Neotoma species (woodrats) in the southwestern United States. Infectious arenavirus was recovered from 14 (3.3%) of 425 woodrats. The virus-positive species included N. albigula in New Mexico and Oklahoma, N. cinerea in Utah, N. mexicana in New Mexico and Utah, and N. micropus in Texas. Analyses of viral nucleocapsid protein gene sequence data indicated that all the isolates were strains of the Whitewater Arroyo virus, an arenavirus previously known only from northwestern New Mexico. Analyses of the sequence data also indicated that there can be substantial genetic diversity among strains of Whitewater Arroyo virus from conspecific woodrats collected from different localities and substantial genetic diversity among strains from different woodrat species collected from the same locality.",

author = "Fulhorst, {C. F.} and Charrel, {R. N.} and Weaver, {S. C.} and Ksiazek, {T. G.} and Bradley, {R. D.} and Milazzo, {M. L.} and Tesh, {R. B.} and Bowen, {M. D.}",

year = "2001",

doi = "10.3201/eid0703.017306",

language = "English",

volume = "7",

pages = "403--407",

journal = "Emerging infectious diseases",

issn = "1080-6040",

number = "3",

}

TY - JOUR

T1 - Geographic distribution and genetic diversity of Whitewater Arroyo virus in the southwestern United States.

AU - Fulhorst, C. F.

AU - Charrel, R. N.

AU - Weaver, S. C.

AU - Ksiazek, T. G.

AU - Bradley, R. D.

AU - Milazzo, M. L.

AU - Tesh, R. B.

AU - Bowen, M. D.

PY - 2001

Y1 - 2001

N2 - The purpose of this study was to extend our knowledge of the geographic distribution and genetic diversity of the arenavirus(es) associated with Neotoma species (woodrats) in the southwestern United States. Infectious arenavirus was recovered from 14 (3.3%) of 425 woodrats. The virus-positive species included N. albigula in New Mexico and Oklahoma, N. cinerea in Utah, N. mexicana in New Mexico and Utah, and N. micropus in Texas. Analyses of viral nucleocapsid protein gene sequence data indicated that all the isolates were strains of the Whitewater Arroyo virus, an arenavirus previously known only from northwestern New Mexico. Analyses of the sequence data also indicated that there can be substantial genetic diversity among strains of Whitewater Arroyo virus from conspecific woodrats collected from different localities and substantial genetic diversity among strains from different woodrat species collected from the same locality.

AB - The purpose of this study was to extend our knowledge of the geographic distribution and genetic diversity of the arenavirus(es) associated with Neotoma species (woodrats) in the southwestern United States. Infectious arenavirus was recovered from 14 (3.3%) of 425 woodrats. The virus-positive species included N. albigula in New Mexico and Oklahoma, N. cinerea in Utah, N. mexicana in New Mexico and Utah, and N. micropus in Texas. Analyses of viral nucleocapsid protein gene sequence data indicated that all the isolates were strains of the Whitewater Arroyo virus, an arenavirus previously known only from northwestern New Mexico. Analyses of the sequence data also indicated that there can be substantial genetic diversity among strains of Whitewater Arroyo virus from conspecific woodrats collected from different localities and substantial genetic diversity among strains from different woodrat species collected from the same locality.

UR - http://www.scopus.com/inward/record.url?scp=0035347595&partnerID=8YFLogxK

U2 - 10.3201/eid0703.017306

DO - 10.3201/eid0703.017306

M3 - Article

C2 - 11384516

AN - SCOPUS:0035347595

SN - 1080-6040

VL - 7

SP - 403

EP - 407

JO - Emerging infectious diseases

JF - Emerging infectious diseases

IS - 3

ER -

Geographic distribution and genetic diversity of Whitewater Arroyo virus in the southwestern United States.

Abstract

Access to Document

Other files and links

Fingerprint

Cite this