Genotype to Phenotype: Insights from Evo-Devo

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


All models of evolution make assumptions about how genotypic variation influences phenotypic variation. As such, they make assumptions about development. The simplest such assumption is that genes contribute additively to phenotype. While this is sometimes a reasonable approximation, there are many cases in which it is not. This article discusses a number of these cases in which development cannot be ignored. These include the quantitative genetics of highly correlated traits, questions about the presence or absence of phenotypic traits in large phylogenetic groups, and questions about the evolution of specific loci that interact epistatically in development.

Original languageEnglish
Title of host publicationEncyclopedia of Evolutionary Biology
PublisherElsevier Inc.
Number of pages6
ISBN (Electronic)9780128004265
ISBN (Print)9780128000496
StatePublished - Apr 14 2016


  • Additive gene action
  • Constraint
  • Development
  • Epistasis
  • Evo-devo
  • Quantitative genetics


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