TY - JOUR
T1 - Functional genomics of root growth and development in Arabidopsis
AU - Iyer-Pascuzzi, Anjali
AU - Simpson, June
AU - Herrera-Estrella, Luis
AU - Benfey, Philip N.
N1 - Funding Information:
We thank members of the Benfey lab for critical reading of the manuscript. Work on root growth and development in the Benfey lab is funded by grants from the NIH (RO1-GM 043778, 5 P50 GM081883) and from the NSF AT2010 and PGRP programs. Funding for nutrient stress responses in the Herrera-Estrella lab is funded by HHMI (55005946) and CONACyT (299/43979).
PY - 2009/4
Y1 - 2009/4
N2 - Roots are vital for the uptake of water and nutrients, and for anchorage in the soil. They are highly plastic, able to adapt developmentally and physiologically to changing environmental conditions. Understanding the molecular mechanisms behind this growth and development requires knowledge of root transcriptomics, proteomics, and metabolomics. Genomics approaches, including the recent publication of a root expression map, root proteome, and environment-specific root expression studies, are uncovering complex transcriptional and post-transcriptional networks underlying root development. The challenge is in further capitalizing on the information in these datasets to understand the fundamental principles of root growth and development. In this review, we highlight progress researchers have made toward this goal.
AB - Roots are vital for the uptake of water and nutrients, and for anchorage in the soil. They are highly plastic, able to adapt developmentally and physiologically to changing environmental conditions. Understanding the molecular mechanisms behind this growth and development requires knowledge of root transcriptomics, proteomics, and metabolomics. Genomics approaches, including the recent publication of a root expression map, root proteome, and environment-specific root expression studies, are uncovering complex transcriptional and post-transcriptional networks underlying root development. The challenge is in further capitalizing on the information in these datasets to understand the fundamental principles of root growth and development. In this review, we highlight progress researchers have made toward this goal.
UR - http://www.scopus.com/inward/record.url?scp=62349137506&partnerID=8YFLogxK
U2 - 10.1016/j.pbi.2008.11.002
DO - 10.1016/j.pbi.2008.11.002
M3 - Review article
C2 - 19117793
AN - SCOPUS:62349137506
SN - 1369-5266
VL - 12
SP - 165
EP - 171
JO - Current Opinion in Plant Biology
JF - Current Opinion in Plant Biology
IS - 2
ER -