Frequencies of micronuclei in bank voles from zones of high radiation at Chornobyl, Ukraine

Brenda E. Rodgers, Robert J. Baker

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

A population of Clethrionomys glareolus (bank vole) from a highly radioactive area within the Chornobyl, Ukraine exclusion zone was sampled in June 1997 and in June and October 1998. Internal radiation doses from radiocesium were estimated to be as high as 8 rads/d. Total dose, which takes into account the internal dose from radiostrontium and the surrounding environment, was estimated to be 15 to 20 rads/d. In contrast, individuals from a reference population lying outside of the exclusion zone registered negligible levels of contamination. We used the micronucleus test in a double-blind study to analyze blood samples from 58 individuals. We scored more than 600,000 polychromatic erythrocytes (PCEs) but could not reject the null hypothesis that the frequency of micronucleated PCEs in voles exposed to radiation was equal to the frequency in unexposed voles. Results of our study stand in sharp contrast to earlier reports of increased frequencies of micronuclei in rodents exposed to fallout of the Chornobyl accident, but with radiation doses that were orders of magnitude lower than those reported here. Radioresistance and experimental methods are possible explanations for these differences in the results.

Original languageEnglish
Pages (from-to)1644-1648
Number of pages5
JournalEnvironmental Toxicology and Chemistry
Volume19
Issue number6
DOIs
StatePublished - 2000

Keywords

  • Chornobyl
  • Clethrionomys glareolus
  • Genotoxicology
  • Micronucleus test
  • Radiation

Fingerprint Dive into the research topics of 'Frequencies of micronuclei in bank voles from zones of high radiation at Chornobyl, Ukraine'. Together they form a unique fingerprint.

Cite this