Face-referenced measurement of perioral stiffness in Parkinson’s disease

S-Y Chu, S M Barlow, Jae Hoon Lee

Research output: Contribution to journalArticlepeer-review


PURPOSE: Perioral biomechanics, labial kinematics, and associated electromyographic signals were sampled and characterized in individuals with Parkinson's disease (PD) as a function of medication state. METHOD: Passive perioral stiffness was sampled using the OroSTIFF system in 10 individuals with PD in a medication ON and a medication OFF state and compared to 10 matched controls. Perioral stiffness, derived as the quotient of resultant force and interoral angle span, was modeled with regression techniques. Labial movement amplitudes and integrated electromyograms from select lip muscles were evaluated during syllable production using a 4-D computerized motion capture system. RESULTS: Multilevel regression modeling showed greater perioral stiffness in patients with PD, consistent with the clinical correlate of rigidity. In the medication-OFF state, individuals with PD manifested greater integrated electromyogram levels for the orbicularis oris inferior compared to controls, w
Original languageEnglish
Pages (from-to)201-212
JournalJournal of Speech, Language, and Hearing Research
StatePublished - 2015


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