Exploration for large-scale stereoselective synthesis of unusual amino acids by using 4-phenyloxazolidin-2-one as a new chiral resolution reagent

Guigen Li; Dinesh Patel; Victor J. Hruby

doi:10.1039/p19940003057

Exploration for large-scale stereoselective synthesis of unusual amino acids by using 4-phenyloxazolidin-2-one as a new chiral resolution reagent

Guigen Li, Dinesh Patel, Victor J. Hruby

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Individual isomers of β-branched α-amino acids have been stereoselective and asymmetrically synthesized in high yield by a new method which uses 4-phenyloxazolidin-2-one as a novel chiral resolution reagent acting simultaneously as the auxiliary.

Original language	English
Pages (from-to)	3057-3059
Number of pages	3
Journal	Journal of the Chemical Society, Perkin Transactions 1
Issue number	21
DOIs	https://doi.org/10.1039/p19940003057
State	Published - 1994

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title = "Exploration for large-scale stereoselective synthesis of unusual amino acids by using 4-phenyloxazolidin-2-one as a new chiral resolution reagent",

abstract = "Individual isomers of β-branched α-amino acids have been stereoselective and asymmetrically synthesized in high yield by a new method which uses 4-phenyloxazolidin-2-one as a novel chiral resolution reagent acting simultaneously as the auxiliary.",

author = "Guigen Li and Dinesh Patel and Hruby, {Victor J.}",

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AU - Patel, Dinesh

AU - Hruby, Victor J.

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AB - Individual isomers of β-branched α-amino acids have been stereoselective and asymmetrically synthesized in high yield by a new method which uses 4-phenyloxazolidin-2-one as a novel chiral resolution reagent acting simultaneously as the auxiliary.

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DO - 10.1039/p19940003057

M3 - Article

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JF - Journal of the Chemical Society - Perkin Transactions 1

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