Exercise-induced vasodilation is associated with menopause stage in healthy middle-aged women

David J. Moore; Joaquin Gonzales; Steven H. Tucker; Steriani Elavsky; David N. Proctor

doi:10.1139/h2012-015

Exercise-induced vasodilation is associated with menopause stage in healthy middle-aged women

David J. Moore, Joaquin Gonzales, Steven H. Tucker, Steriani Elavsky, David N. Proctor

Kinesiology and Sport Management

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: To determine whether leg exercise hemodynamic responses are menopause stage-dependent in healthy, middle-aged women. Methods: Women were divided into early perimenopausal (n = 16), late perimenopausal (n = 12), and early postmenopausal (n=11) groups based on self-reported bleeding history using the Stages of Reproductive Aging Workshop (STRAW) criteria. Femoral artery blood flow (FBF), mean arterial pressure (MAP), and femoral vascular conductance (FVC) were measured during graded single-leg knee extensor exercise. Results: FBF and FVC at rest and during very light work rates (0 and 5 Watts) were similar among all three menopause stage groups. At 10 Watts, FBF and FVC were significantly higher (P < 0.05) in early perimenopausal compared with late perimenopausal women At higher work rates (15-25 Watts) FBF and FVC were similar between late perimenopausal and early postmenopausal groups, but higher (P<0.05) in early perimenopausal women as compared with the other two

Original language	English
Pages (from-to)	418-424
Journal	Applied Physiology, Nutrition and Metabolism
DOIs	https://doi.org/10.1139/h2012-015
State	Published - Apr 2012

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title = "Exercise-induced vasodilation is associated with menopause stage in healthy middle-aged women",

abstract = "Objective: To determine whether leg exercise hemodynamic responses are menopause stage-dependent in healthy, middle-aged women. Methods: Women were divided into early perimenopausal (n = 16), late perimenopausal (n = 12), and early postmenopausal (n=11) groups based on self-reported bleeding history using the Stages of Reproductive Aging Workshop (STRAW) criteria. Femoral artery blood flow (FBF), mean arterial pressure (MAP), and femoral vascular conductance (FVC) were measured during graded single-leg knee extensor exercise. Results: FBF and FVC at rest and during very light work rates (0 and 5 Watts) were similar among all three menopause stage groups. At 10 Watts, FBF and FVC were significantly higher (P < 0.05) in early perimenopausal compared with late perimenopausal women At higher work rates (15-25 Watts) FBF and FVC were similar between late perimenopausal and early postmenopausal groups, but higher (P<0.05) in early perimenopausal women as compared with the other two",

author = "Moore, {David J.} and Joaquin Gonzales and Tucker, {Steven H.} and Steriani Elavsky and Proctor, {David N.}",

year = "2012",

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doi = "10.1139/h2012-015",

language = "English",

pages = "418--424",

journal = "Applied Physiology, Nutrition and Metabolism",

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T1 - Exercise-induced vasodilation is associated with menopause stage in healthy middle-aged women

AU - Moore, David J.

AU - Gonzales, Joaquin

AU - Tucker, Steven H.

AU - Elavsky, Steriani

AU - Proctor, David N.

PY - 2012/4

Y1 - 2012/4

N2 - Objective: To determine whether leg exercise hemodynamic responses are menopause stage-dependent in healthy, middle-aged women. Methods: Women were divided into early perimenopausal (n = 16), late perimenopausal (n = 12), and early postmenopausal (n=11) groups based on self-reported bleeding history using the Stages of Reproductive Aging Workshop (STRAW) criteria. Femoral artery blood flow (FBF), mean arterial pressure (MAP), and femoral vascular conductance (FVC) were measured during graded single-leg knee extensor exercise. Results: FBF and FVC at rest and during very light work rates (0 and 5 Watts) were similar among all three menopause stage groups. At 10 Watts, FBF and FVC were significantly higher (P < 0.05) in early perimenopausal compared with late perimenopausal women At higher work rates (15-25 Watts) FBF and FVC were similar between late perimenopausal and early postmenopausal groups, but higher (P<0.05) in early perimenopausal women as compared with the other two

AB - Objective: To determine whether leg exercise hemodynamic responses are menopause stage-dependent in healthy, middle-aged women. Methods: Women were divided into early perimenopausal (n = 16), late perimenopausal (n = 12), and early postmenopausal (n=11) groups based on self-reported bleeding history using the Stages of Reproductive Aging Workshop (STRAW) criteria. Femoral artery blood flow (FBF), mean arterial pressure (MAP), and femoral vascular conductance (FVC) were measured during graded single-leg knee extensor exercise. Results: FBF and FVC at rest and during very light work rates (0 and 5 Watts) were similar among all three menopause stage groups. At 10 Watts, FBF and FVC were significantly higher (P < 0.05) in early perimenopausal compared with late perimenopausal women At higher work rates (15-25 Watts) FBF and FVC were similar between late perimenopausal and early postmenopausal groups, but higher (P<0.05) in early perimenopausal women as compared with the other two

U2 - 10.1139/h2012-015

DO - 10.1139/h2012-015

M3 - Article

SP - 418

EP - 424

JO - Applied Physiology, Nutrition and Metabolism

JF - Applied Physiology, Nutrition and Metabolism

ER -

Exercise-induced vasodilation is associated with menopause stage in healthy middle-aged women

Abstract

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