TY - JOUR
T1 - Evidence supporting vertical transmission of Salmonella in dairy cattle
AU - Hanson, D. L.
AU - Loneragan, G. H.
AU - Brown, T. R.
AU - Nisbet, D. J.
AU - Hume, M. E.
AU - Edrington, T. S.
N1 - Publisher Copyright:
Copyright © Cambridge University Press 2015.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - We set out to investigate whether Salmonella enterica could be recovered from various tissues of viable neonatal calves immediately following parturition. Eleven samples were aseptically collected from each of 20 calves and consisted of both left and right subiliac and prescapular lymph nodes (LN), mesenteric LN, spleen and liver, as well as intestinal tissue (including luminal contents) from the small intestine, caecum, spiral colon and rectum. In addition, a faecal sample was collected from 19 of the dams. Salmonella was recovered from at least one sample from 10 of the 20 neonates. Across all calves, Salmonella was recovered from 12.7% of all samples and from LN in particular, Salmonella was recovered from 10.0%, 5.0%, and 5.0% of subiliac, prescapular, and mesenteric LN, respectively. Within calves, Salmonella was recovered from 0% to 73% of samples and across tissues, estimates of Salmonella prevalence were greatest in the caecum (30%) but was never recovered from the right pre-scapular LN. These data provide evidence of vertical transmission from a dam to her fetus such that viable calves are born already infected and thereby not requiring faecal-oral exposure for transmission. This new knowledge ought to challenge - or at least add to - existing paradigms of Salmonella transmission dynamics within cattle herds.
AB - We set out to investigate whether Salmonella enterica could be recovered from various tissues of viable neonatal calves immediately following parturition. Eleven samples were aseptically collected from each of 20 calves and consisted of both left and right subiliac and prescapular lymph nodes (LN), mesenteric LN, spleen and liver, as well as intestinal tissue (including luminal contents) from the small intestine, caecum, spiral colon and rectum. In addition, a faecal sample was collected from 19 of the dams. Salmonella was recovered from at least one sample from 10 of the 20 neonates. Across all calves, Salmonella was recovered from 12.7% of all samples and from LN in particular, Salmonella was recovered from 10.0%, 5.0%, and 5.0% of subiliac, prescapular, and mesenteric LN, respectively. Within calves, Salmonella was recovered from 0% to 73% of samples and across tissues, estimates of Salmonella prevalence were greatest in the caecum (30%) but was never recovered from the right pre-scapular LN. These data provide evidence of vertical transmission from a dam to her fetus such that viable calves are born already infected and thereby not requiring faecal-oral exposure for transmission. This new knowledge ought to challenge - or at least add to - existing paradigms of Salmonella transmission dynamics within cattle herds.
KW - Epidemiology
KW - Salmonella
KW - zoonoses
UR - http://www.scopus.com/inward/record.url?scp=84971602512&partnerID=8YFLogxK
U2 - 10.1017/S0950268815002241
DO - 10.1017/S0950268815002241
M3 - Article
C2 - 26419321
AN - SCOPUS:84971602512
SN - 0950-2688
VL - 144
SP - 962
EP - 967
JO - Epidemiology and Infection
JF - Epidemiology and Infection
IS - 5
ER -