Electroporation dynamics in biological cells subjected to ultrafast electrical pulses: A numerical simulation study

R. P. Joshi, K. H. Schoenbach

Research output: Contribution to journalArticlepeer-review

123 Scopus citations

Abstract

A model analysis of electroporation dynamics in biological cells is investigated based on the Smoluchowski equation. The Smoluchowski equation that governs the pore dynamics is given in terms of the pore density distribution function n(r,t). One of the objectives is to obtain prediction and a qualitative understanding of the cellular response to short, electric pulses by taking into account of the growth and resealing dynamics. The physical processes of pore generation, drift, and diffusion in r space are comprehensively included.

Original languageEnglish
Pages (from-to)1025-1033
Number of pages9
JournalPhysical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
Volume62
Issue number1 B
DOIs
StatePublished - Jul 2000

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