A model analysis of electroporation dynamics in biological cells is investigated based on the Smoluchowski equation. The Smoluchowski equation that governs the pore dynamics is given in terms of the pore density distribution function n(r,t). One of the objectives is to obtain prediction and a qualitative understanding of the cellular response to short, electric pulses by taking into account of the growth and resealing dynamics. The physical processes of pore generation, drift, and diffusion in r space are comprehensively included.
|Number of pages||9|
|Journal||Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics|
|Issue number||1 B|
|State||Published - Jul 2000|