Electrochemical Aziridination by Alkene Activation Using a Sulfamate as the Nitrogen Source

Jin Li, Wenhao Huang, Jingzhi Chen, Lingfeng He, Xu Cheng, Guigen Li

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Abstract

The first direct aziridination of triaryl-substituted alkenes was achieved by means of an electrochemical process that could extend to multisubstituted styrenes. Specifically, hexafluoroisopropanol sulfamate was used as a nucleophilic nitrogen source. Mechanistic experiments suggest that this electrochemical process proceeds by stepwise formation of two C−N bonds through reactions between cationic carbon species and the sulfamate.

Original languageEnglish
Pages (from-to)5695-5698
Number of pages4
JournalAngewandte Chemie - International Edition
Volume57
Issue number20
DOIs
StatePublished - May 14 2018

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Keywords

  • alkenes
  • aziridines
  • electrochemistry
  • radicals
  • synthetic methods

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