Efficient nucleophilic substitution reactions of highly functionalized allyl halides in ionic liquid media

S. R.S.Saibabu Kotti, Xin Xu, Guigen Li, Allan D. Headley

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Nucleophilic substitution reactions of highly functionalized allyl halides with three anions, N3-, AcO-, and PhSO 2-, in ionic liquid media were conducted. The ionic liquid, [Bmim][BF4], was found to be superior to classical organic solvents to give higher yields and faster reaction rates. The resulting products belong to multifunctionalized trisubstituted α, β-unsaturated ketones, which are useful building blocks for organic synthesis.

Original languageEnglish
Pages (from-to)1427-1431
Number of pages5
JournalTetrahedron Letters
Volume45
Issue number7
DOIs
StatePublished - Feb 9 2004

Keywords

  • Halides
  • Ionic liquid
  • S2 reaction
  • α,β-Unsaturated ketone

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