Efficient domino approaches to multifunctionalized fused pyrroles and dibenzo[ b, e ][1,4]diazepin-1-ones

Bo Jiang; Qiu Yun Li; Hao Zhang; Shu Jiang Tu; Suresh Pindi; Guigen Li

doi:10.1021/ol203166c

Efficient domino approaches to multifunctionalized fused pyrroles and dibenzo[ b, e ][1,4]diazepin-1-ones

Bo Jiang, Qiu Yun Li, Hao Zhang, Shu Jiang Tu, Suresh Pindi, Guigen Li

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

Efficient domino approaches for the synthesis of multifunctionalized tricyclic fused pyrroles and dibenzo[b,e][1,4]diazepin-1-ones have been established. The reaction pathways were controlled by varying enaminones with different substituted patterns to give a series of new fused pyrroles and dibenzo[b,e][1,4]diazepin-1-ones selectively. The complete anti diastereoselectivity was achieved for the first reaction.

Original language	English
Pages (from-to)	700-703
Number of pages	4
Journal	Organic Letters
Volume	14
Issue number	3
DOIs	https://doi.org/10.1021/ol203166c
State	Published - Feb 3 2012

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AU - Tu, Shu Jiang

AU - Pindi, Suresh

AU - Li, Guigen

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AB - Efficient domino approaches for the synthesis of multifunctionalized tricyclic fused pyrroles and dibenzo[b,e][1,4]diazepin-1-ones have been established. The reaction pathways were controlled by varying enaminones with different substituted patterns to give a series of new fused pyrroles and dibenzo[b,e][1,4]diazepin-1-ones selectively. The complete anti diastereoselectivity was achieved for the first reaction.

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Efficient domino approaches to multifunctionalized fused pyrroles and dibenzo[ b, e ][1,4]diazepin-1-ones

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