Effects of suture position on left ventricular fluid mechanics under mitral valve edge-to-edge repair

Dongxing Du, Song Jiang, Ze Wang, Yingying Hu, Zhaoming He

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Mitral valve (MV) edge-to-edge repair (ETER) is a surgical procedure for the correction of mitral valve regurgitation by suturing the free edge of the leaflets. The leaflets are often sutured at three different positions: central, lateral and commissural portions. To study the effects of position of suture on left ventricular (LV) fluid mechanics under mitral valve ETER, a parametric model of MV-LV system during diastole was developed. The distribution and development of vortex and atrio-ventricular pressure under different suture position were investigated. Results show that the MV sutured at central and lateral in ETER creates two vortex rings around two jets, compared with single vortex ring around one jet of the MV sutured at commissure. Smaller total orifices lead to a higher pressure difference across the atrio-ventricular leaflets in diastole. The central suture generates smaller wall shear stresses than the lateral suture, while the commissural suture generated the minimum wall shear stresses in ETER.

Original languageEnglish
Pages (from-to)155-161
Number of pages7
JournalBio-Medical Materials and Engineering
Volume24
Issue number1
DOIs
StatePublished - 2014

Keywords

  • Left ventricular
  • atrio-ventricular pressure
  • edge to edge repair (ETER)
  • mitral valve
  • vortex
  • wall shear stress

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