Effect of green tea and Tai Chi on bone health in postmenopausal osteopenic women: A 6-month randomized placebo-controlled trial

C. L. Shen, M. C. Chyu, J. K. Yeh, Y. Zhang, B. C. Pence, C. K. Felton, J. M. Brismée, B. H. Arjmandi, S. Doctolero, J. S. Wang

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Summary Postmenopausal women with osteopenia received green tea polyphenols (GTP) SUPPL.ement and/or Tai Chi exercise for 6 months. Bone turnover biomarkers, calcium metabolism, and muscle strength were measured. This study showed that GTP SUPPL.ementation and Tai Chi exercise increased bone formation biomarkers and improved bone turnover rate. Tai Chi exercise increased serum parathyroid hormone. GTP SUPPL.ementation, Tai Chi exercise, and the combination of the two all improved muscle strength in postmenopausal women with osteopenia. Introduction This study evaluated the effect of GTP SUPPL.ementation and Tai Chi (TC) exercise on serum markers of bone turnover (bone-specific alkaline phosphatase, BAP, and tartrate-resistant acid phosphatase, TRAP), calcium metabolism, and muscle strength in postmenopausal osteopenic women. Methods One hundred and seventy-one postmenopausal osteopenic women were randomly assigned to four groups: (1) placebo (500 mg starch/day), (2) GTP (500 mg GTP/day), (3) placebo + TC (placebo plus TC training at 60 min/session, three sessions/week), and (4) GTP + TC (GTP plus TC training). Overnight fasting blood and urine samples were collected at baseline, 1, 3, and 6 months for biomarker analyses. Muscle strength was evaluated at baseline, 3, and 6 months. One hundred and fifty subjects completed the 6-month study. Results Significant increases in BAP level due to GTP intake (at 1 month) and TC (at 3 months) were observed. Significant increases in the change of BAP/TRAP ratio due to GTP (at 3 months) and TC (at 6 months) were also observed. Significant main effect of TC on the elevation in serum parathyroid hormone level was observed at 1 and 3 months. At 6 months, muscle strength significantly improved due to GTP, TC, and GTP + TC interventions. Neither GTP nor TC affected serum TRAP, serum and urinary calcium, and inorganic phosphate. Conclusion In summary, GTP SUPPL.ementation and TC exercise increased BAP and improved BAP/TRAP ratio. TC exercise increased serum parathyroid hormone. GTP SUPPL.ementation, TC exercise, and the combination of the two all improved muscle strength in postmenopausal women with osteopenia.

Original languageEnglish
Pages (from-to)1541-1552
Number of pages12
JournalOsteoporosis International
Volume23
Issue number5
DOIs
StatePublished - May 2012

Keywords

  • Bone turnover biomarker
  • Calcium metabolism
  • Green tea
  • Mind-body exercise
  • Muscle strength
  • Osteoporosis
  • Tai Chi

Fingerprint

Dive into the research topics of 'Effect of green tea and Tai Chi on bone health in postmenopausal osteopenic women: A 6-month randomized placebo-controlled trial'. Together they form a unique fingerprint.

Cite this