TY - JOUR
T1 - Dynamic reoptimization of a fed-batch fermentor
AU - Iyer, Mahesh S.
AU - Wiesner, Theodore F.
AU - Rhinehart, R. Russell
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1999/4/5
Y1 - 1999/4/5
N2 - Traditionally, fed-batch biochemical process optimization and control use complicated models and off-line optimizers with no on-line model adaptation and re-optimization. This work demonstrates the applicability, effectiveness, and economic potential, of a simple phenomenological model for modeling, and a novel optimizer for on-line re-optimization and control of an aerobic fed-batch fermentor.
AB - Traditionally, fed-batch biochemical process optimization and control use complicated models and off-line optimizers with no on-line model adaptation and re-optimization. This work demonstrates the applicability, effectiveness, and economic potential, of a simple phenomenological model for modeling, and a novel optimizer for on-line re-optimization and control of an aerobic fed-batch fermentor.
KW - Dynamic re-optimization
KW - Fed-batch fermentor
KW - Model re- parametrization
KW - Process-model mismatch
UR - http://www.scopus.com/inward/record.url?scp=0033526125&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1097-0290(19990405)63:1<10::AID-BIT2>3.0.CO;2-C
DO - 10.1002/(SICI)1097-0290(19990405)63:1<10::AID-BIT2>3.0.CO;2-C
M3 - Article
C2 - 10099577
AN - SCOPUS:0033526125
VL - 63
SP - 10
EP - 21
JO - Biotechnology and Bioengineering
JF - Biotechnology and Bioengineering
SN - 0006-3592
IS - 1
ER -