Abstract
A novel synergistic rhodium/copper catalysis has been established,
enabling de-diazotized cycloadditions of 1,5-enynes and
alpha-diazocarbonyls toward the selective formation of densely
functionalized benzo[b] fluorenes and 2-naphthalenylmethanones.
alpha-Aryldiazoesters result in the formation of triple C-C bonds
through bimetallic catalysis whereas a range of functionalized
naphthalenes with a 1,5-dicarbonyl unit were accomplished using
alpha-diazocarbonyls without any substituent at the alpha-position,
indicating that substituents at the alpha-position of the
alpha-diazocarbonyl unit could control the selectivity of the reaction.
Original language | English |
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Pages (from-to) | 11943-11946 |
Journal | Chemical Communications |
State | Published - 2016 |