Abstract
We report the first example of difluoroalkylation/C-H annulation cascade
reactions of cyclopropyl olefins induced by visible-light photoredox
catalysis regioselectively affording partially hydrogenated naphthalenes
and quinolines with a variety of difluorinated side chains. The
alkylation reagent could be extended to monofluoro and trifluoro
reagents, nitrite and malonate. The regioselectivity was investigated by
means of density functional theory calculations.
Original language | English |
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Pages (from-to) | 9992-10001 |
Journal | Journal of Organic Chemistry |
State | Published - Oct 2016 |