TY - JOUR
T1 - Development of a pulsed radio frequency glow discharge for three-dimensional elemental surface imaging. 1. Application to biopolymer analysis
AU - Gamez, Gerardo
AU - Ray, Steven J.
AU - Andrade, Francisco J.
AU - Webb, Michael R.
AU - Hieftje, Gary M.
PY - 2007/2/15
Y1 - 2007/2/15
N2 - Glow discharge optical emission spectrometry has cemented itself as an important surface elemental analysis technique in part because of its superb depth resolution (on the order of single nanometers). However, very few studies have explored the ability of the glow discharge to provide laterally resolved elemental information. In the present study, an end-on-viewed pulsed radio frequency glow discharge is coupled to a monochromatic imaging spectrometer to provide lateral surface imaging. The performance of the technique is demonstrated with etched copper circuits on fiber-glass substrates, and it is shown how several operating parameters including pressure, pulsed mode operation, and time-resolved detection affect the lateral surface resolution. In addition, because a pulsed radio frequency glow discharge offers elemental information on nonconducting samples, the technique is applied to the three-dimensional elemental analysis of proteins on blotting substrates. Several alternative sample types are also examined, including photographic film and glass.
AB - Glow discharge optical emission spectrometry has cemented itself as an important surface elemental analysis technique in part because of its superb depth resolution (on the order of single nanometers). However, very few studies have explored the ability of the glow discharge to provide laterally resolved elemental information. In the present study, an end-on-viewed pulsed radio frequency glow discharge is coupled to a monochromatic imaging spectrometer to provide lateral surface imaging. The performance of the technique is demonstrated with etched copper circuits on fiber-glass substrates, and it is shown how several operating parameters including pressure, pulsed mode operation, and time-resolved detection affect the lateral surface resolution. In addition, because a pulsed radio frequency glow discharge offers elemental information on nonconducting samples, the technique is applied to the three-dimensional elemental analysis of proteins on blotting substrates. Several alternative sample types are also examined, including photographic film and glass.
UR - http://www.scopus.com/inward/record.url?scp=33847211082&partnerID=8YFLogxK
U2 - 10.1021/ac061361l
DO - 10.1021/ac061361l
M3 - Article
C2 - 17243768
AN - SCOPUS:33847211082
VL - 79
SP - 1317
EP - 1326
JO - Analytical Chemistry
JF - Analytical Chemistry
SN - 0003-2700
IS - 4
ER -